CAS:743420-02-2丨Chidamide

Sidarbenamine inhibits the cell cycle of lymphoid and hematologic tumors and induces tumor cell apoptosis through inhibition of specific HDAC subtypes and the resulting regulation of chromatin remodeling and gene transcription (i.e. epigenetic regulation). Inducing and enhancing the tumor killing effect mediated by natural killer cells (NK) and antigen-specific cytotoxic TChemicalbook cells (CTL) and inhibiting the inflammatory response of tumor pathological tissue can not only directly contribute to the efficacy of circulating tumor cells and local lesions in T lymphoma. It may also be used to induce and enhance the overall regulatory activity of anti-tumor cellular immunity against other tumor types.

CAS:743420-02-2

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